“In multiple sclerosis, the immune system goes rogue, improperly attacking the body’s own central nervous system. Mobility problems and cognitive impairments may arise as the nerve cells become damaged.
In a new study, researchers from the University of Pennsylvania and co-investigators have identified a key protein that is able to reduce the severity of a disease equivalent to MS in mice. This molecule, Del-1, is the same regulatory protein that has been found to prevent inflammation and bone loss in a mouse model of gum disease.
“We see that two completely different disease entities share a common pathogenic mechanism,” said George Hajishengallis, a professor of microbiology in Penn’s School of Dental Medicine and an author on the study.”
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