“Periodontitis, a severe form of gum disease, doesn’t just cause soft-tissue inflammation and bleeding. It also destroys the bone that supports the teeth. If it progresses unchecked, it can lead to tooth loss and is even associated with systemic inflammatory conditions like atherosclerosis and rheumatoid arthritis.
A new study led by University of Pennsylvania School of Dental Medicine researchers demonstrates that a protein called Del-1, can inhibit bone loss associated with periodontitis. They also found the protein curbs the activity of osteoclasts, cells that absorb bone tissue, leading to a mechanistic explanation of how Del-1 can prevent periodontal bone loss.”
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