“Health conditions that involve inflammation run the gamut, from multiple sclerosis and lupus to arthritis, diabetes, and cancer. While inflammation can serve as a normal response to help the body deal with injury or infection, problems arise when it persists, potentially harming surrounding tissues.

To prevent or ameliorate this damage, the body relies on a strategy to actively clear inflammation. “It’s not just extinguishing the fire of inflammation,” says Penn’s George Hajishengallis. “You also have to return things to the way they were before the inflammatory destruction.”

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