“Up until recently it has been a bit of a mystery as to how bacterium Porphyromonas gingivalis were able to wreck such havoc in the mouth, and how exactly they were able to trigger periodontitis, despite being present in relatively low numbers in the sub gingival crevice. Now researchers have discovered that P. gingivalis is able to reprogram the immune cells that normally protect the sub gingival crevice, into creating conditions it finds more favourable.
The reprogrammed immune cells effectively persuade more immune cells to follow their lead, prompting the usually benign bacterial residents of the sub gingival crevice to rise up and defend their realm, which in turn leads to inflammation of the supportive structures of the tooth.”
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